Ross, I find painful infusion sets are really rare for me, I’ve always suspected the cause to be a case of an infusion set literally getting on my nerves. If you’re getting pain with every set, definitely try changing to another kind. Pain can also be caused by the cannula being too long – ie you’ve got a cannula length designed to get through the hide of a sumo wrestler and you barely have enough body fat to survive a Scottish summer so the cannula is poking too deeply into you.